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严格控制饮食双打蠕虫的寿命

新闻来源:admin 发布时间:2018-09-17

Taking food away from C。 elegans in larval stages suspends their development; while they still wiggle around and look for food, they are in a state of arrested development。 However, when food becomes plentiful again, they start to develop normally –; but live twice as long。

This shows the nematode worm C。 elegans with muscle cells fluorescently labeled in green and germ cells fluorescently labeled in red。 These cells and others pause at a checkpoint in development and slow their aging when worms encounter a period of starvation。 Credit: David Sherwood Lab, Duke University

This remarkably ****** way of achieving longevity is not entirely surprising。 It has been known for quite a while that a low intake of nutrients and reduced cellular activity are generally linked with longevity –; but doubling the lifespan only through a strict but temporary diet, that’;s something quite surprising。

“;It is possible that low-nutrient diets set off the same pathways in us to put our cells in a quiescent state,”; said David R。 Sherwood, an associate professor of biology at Duke University。 “;The trick is to find a way to pharmacologically manipulate this process so that we can get the anti-aging benefits without the pain of diet restriction。”;

Sherwood and his colleagues from Duke University took a myriad of creatures and deprived them of food, in order to study the effects on longevity。 They studied rats, mice, yeast, flies, spiders, fish, monkeys and worms; the effects on longevity varied between 30 percent to 200 percent, but in all cases, the lifespan was increased。 Caenorhabditis elegans, a non-parasitic worm showed the most promise。

本文源自: 环亚娱乐



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